What causes people to be depressed?

Many things can cause people to become depressed. Stress, health, hormones changes can cause this as well as things like abuse of alcohol and drugs. Medical conditions like hypothyroidism can also cause similar symptoms to depression. Basic elements such as sleep and diet can also affect brain function and mood. Physical, sexual, or emotional abuse can cause depression. Difficult life circumstances such as grief and loss can cause people to be depressed.